Chetan Singh Chauhan
Pharmacy
September 2021
Delivery of poorly water soluble drugs is a major challenge for pharmaceutical formulation scientist. Hydrophobic drugs due to its low bioavailability exhibits unpredictable absorption patterns. Surfactants which upon self assembly results into formation of colloidal sized structures called as micelles are excellent solubilizing agents. This review illustrates the theoretical concepts of Micellar soubilization like solubilization capacity (χ), micelle water partition coefficient (K) and thermodynamics of Micellar solubilization.
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© Airo Journals 2021
