Ritesh Bhawsar
Biotechnology
May 2022
The goal of the study was to look at the phytochemistry and effects of Rauwolfia serpentina methanolic root extract (MREt) on alloxan-induced diabetic Wister male mice. Mice were separated into diabetic (refined water at 1 mL/kg), negative (0.05 percent dimethyl sulfoxide at 1 mL/kg), and positive (glibenclamide at 5 mg/kg) controls, as well as three experimental groups (MREt at 10, 30, and 60 mg/kg). For 14 days, all drugs were taken orally. MREt demonstrated the existence of alkaloids, carbohydrates, flavonoids, glycosides, cardiovascular glycosides, phlobatannins, pitches, saponins, steroids, tannins, and triterpenoids subjectively, while quantitatively separate was rich in all out phenols. The flavonoids, saponins, and alkaloids in root powder are still floating around. When compared to diabetic control, MREt was discovered to be successful in further developing body loads, glucose and insulin levels, insulin/glucose proportion, glycosylated and all out haemoglobin in test bunches.
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© Airo Journals 2021
