Ratna Bali Singh
Zoology
June 2021
Artificial skin models have drawn interest as an alternative to animal testing for determining the safety and toxicity of items since 2013, since ethics for animal experimentation have been reinforced in the European Union. Different artificial skin models have been created by mixing various biomaterials and human cells as well as employing a number of processes, including freeze-drying, 3-D printing, electro spinning, and microfluidic system, driven by regulatory authorities and industrial needs. For the evaluation of safety and efficacy in the cosmetic and pharmaceutical industries as well as for the fundamental studies on cell to cell interactions, cell to extracellular matrix interactions, tissue formation and development, intricately designed artificial skin models that closely resemble human skin can be highly valuable and effective tools. This article summarizes several manufacturing methods for synthetic skin models and their primary uses.
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© Airo Journals 2021
