Priyanka Mankar
Chemistry
March 2022
Several novel tetrazole and 1, 3-oxazepine derivatives have been synthesised in the current work, beginning with the reaction of L-ascorbic acid in dry acetone in the presence of dry hydrogen chloride to produce the acetyl. The latter's reaction with p-nitrobenzoyl chloride in pyridine produced an ester, which when dissolved in ethanol with (65%) acetic acid produced a glycol molecule. Glycol and sodium periodate were combined to create the aldehyde compound in distilled water. By reacting 2-phenyl 4H-benzo[d][1,3]oxazin-4-one with glycine and glacial acetic acid, the chemicals 2-(4-oxo-2-phenylquinazolin3 (4H)-yl) acetic acid and 2-(1,3-dioxoisoindolin-2-yl) acetic acid were created. By reacting substances with thionyl chloride and subsequently condensing those substances with hydrazine hydrate, substances were produced. By reacting hydrazide and aldehyde molecules, the isomethene compounds were created. By condensing an amine molecule with sodium azide and phthalic anhydride, respectively, oxyazepine and tetrazole compounds were created. Physical parties and spectroscopic techniques, including the Fourier transform, were used to identify the produced compounds' structures.
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