Rishi Kumar Mishra
Pharmacy
December 2022
Atenolol (ATN), lisinopril (LISI), hydrochlorothiazide (HCTZ), enalapril maleate (ENA), amlodipine besylate (AMLO), losartan potassium (LOSA), valsartan (VAL), and atorvastatin calcium (ATOR) are eight of the most commonly prescribed medications for cardiovascular diseases, and each is discussed individually here. A ZORBAX Rx-C8 segment (250 x 4.6 x 5 l m molecule size) was employed in a portable phase of acetonitrile and 10 mM dipotassium hydrogen phosphate cradle (pH 2.2 modified with orthophosphoric corrosive) with an inclination customized. At a flow rate of 1.0 mL min-1, a quantitative analysis was performed at 210 nm. Acceptance of the regulations at the Global Meeting on Harmonization validated the approach as a viable means of providing quantitative drug assurance. In light of its robustness, specificity, precision, and accuracy, the method can be used for routine quality control assessment of 15 mix pharmaceutical definitions
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