Deeparchan Ray
Biomedical Science
March 2025
This research examines the possibility of green-synthesized carbon dots (C-dots) as a novel, safer method of bone sarcoma treatment, where they are found to be biocompatible, less toxic, and environmentally friendly. These green C-dots are synthesized from natural plant extracts and show excellent wound healing capacity, with a 100% healing rate by Day 14, compared to other nanoparticles like chemogenic C-dots, silver, and gold nanoparticles. Their strong antibacterial activity, combined with enhanced physicochemical properties—such as reduced particle size, stability in aqueous media, and functional surface groups—position green C-dots as a strong contender for targeted, non-surgical cancer treatments. Additionally, the C-dots display robust antimicrobial action against E. coli, S. aureus, and P. aeruginosa, indicating their promise in infection prevention and regenerative medicine. Having fewer side effects than conventional chemotherapy agents, green-synthesized C-dots present a novel and affordable option for bone sarcoma therapy and have the potential to greatly decrease the toxicity of traditional treatments. The results highlight the potential clinical utility of green C-dots for cancer therapy and regenerative medicine.
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